Relaxant Effects of Aflatoxins on Isolated Guinea Pig Trachea
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چکیده
منابع مشابه
Relaxant effect of pioglitazone on the guinea-pig isolated trachea through the modulation of endogenous prostaglandins
Thiazolidinediones are commonly used anti-diabetic drugs. Owing to the anti-inflammatory action of TZDs as a result of there action on the PPAR gamma receptor and a proposed action on the prostaglandins, these drugs can be tried in the acute exacerbations of COPD that are also commonly found among diabetic patients. An experimental study of one week was carried out at animal house of Army Medic...
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In the previous studies the relaxant, anti-cholinergic (functional antagonism) and anti-histaminic effects of Nigella sativa have been demonstrated on guinea pig tracheal chains. To elucidate the main substance responsible for the relaxant effect of this plant, the effect of thymoquinone, one of the main constituent of Nigella sativa was examined in this study. The bronchodilatory effects of th...
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The structure-activity relationships between flavonoids and their tracheal relaxant action are little known. In the present study, 26 natural and synthetic flavonoids, divided into the five classes of flavones, flavonols, flavanones, isoflavones, and chalcones, were tested, and their IC (50) values were determined. The IC (50) values of these five classes indicated that flavones were more poten...
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Achillea wilhelmsii have been used in folk remedies. The relaxant effects of the extractof A. wilhelmsii on tracheal chains of guinea pigs were examined. The relaxant effects offour cumulative concentrations of the extract, theophylline and saline were examined bytheir relaxant effects on precontracted tracheal chains of guinea pig by KCl (group 1), 10 μMmethacholine (group 2), incubated tissue...
متن کاملpossible relaxant effects of thymoquinone on guinea pig tracheal chain
in the previous studies the relaxant, anti-cholinergic (functional antagonism) and anti-histaminic effects of nigella sativa have been demonstrated on guinea pig tracheal chains. to elucidate the main substance responsible for the relaxant effect of this plant, the effect of thymoquinone, one of the main constituent of nigella sativa was examined in this study. the bronchodilatory effects of th...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2000
ISSN: 1096-0929
DOI: 10.1093/toxsci/55.1.162